During this period he developed an interest in non-adherence in young adult transplant recipients and transition of care from paediatric to adult care. He established a joint transition process with Birmingham Children's Hospital. In 2002, Dr Harden joined the Oxford Kidney Unit and Transplant Centre and has continued to pursue his interest in transition, having established joint clinics with Great Ormond Street and Evelina Children's Hospitals in London. He is clinical advisor to the National Health Service in the UK on adolescent transition and young adult services in patients with ESRD. He runs a unique community-based young adult transplant service in Oxford. In addition Paul Harden is interested in malignancy post-transplantation and the impact of targeted immunosuppression reduction. He is Chief Investigator of the RESCUE (UK) trial of immunosuppression modulation for squamous cell skin cancer post-transplantation. He is currently working with a European consortium on development of a trial of cell therapy to allow immunosuppression reduction. Dr. Paul Harden is the very well known nephrologist in Belarus since 2005. He provided great help in developing nephrology, dialysis, LRKTx, paediatric KTx in Belarus in the frame of ISN Minsk-Oxford Renal Sister Center (RSCP) Link. He is currently keeps the position of the Chair of RSCP in the ISN as well as the Co-Chair of ISN - TTS Sister Transplant Center Program.